Side-by-side photos of the first celebrities to admit to using Ozempic and GLP-1

Some days, it feels like GLP-1s have been around forever. To be fair, these types of drugs have been in the making since the early 2000s, according to the 2025 report. condition In pharmaceutical research. But drugs like Ozempic, Wegovy, and Mounjaro started making waves about a decade ago.

Initially, GLP-1s were targeted to help diabetics better control their blood sugar. However, doctors and patients quickly noticed a trend: individuals who injected themselves with GLP-1s began to lose weight as a side effect. It was an unexpected result, and it caught the attention of the public and the eyes of Hollywood.

As news spread about this new weight loss method, celebrities began using GLP-1s. Some have kept quiet about their experiences, but others have admitted to jumping on the trend.

Who was one of the first to come out and say, “Yes, I tried it”? Quite a few familiar faces you may have seen on screen.

Model and reality TV star Brooks Nader may have an on-again, off-again relationship with Ozempic. In 2024, Us Weekly “I took a few from it when it first came out,” she was quoted as saying. But she confirmed to the magazine that she had stopped.

In 2024 Tik TokNader’s sisters jokingly stated that although Nader said she lost 20 pounds through exercise, she was actually using Ozempic. The following year, her family became more concerned and stepped in to ask her to give up GLP-1 (via Page six). Nader admitted to microdosing GLP-1s (taking less than the normally prescribed dose), but said she wouldn’t stop, claiming she was under too much stress to stay thin.

Back in 2022, businessman and public figure Elon Musk attributed his lean body to a combination of taking GLP-1 Wegovy and fasting (via University of Colorado Anschutz). Musk showed his support for GLP-1 two years later in tweet: “Nothing would do more to improve the health, lifespan, and quality of life of Americans than making GLP inhibitors very low cost.”

And in 2024 another tweetshared a photo of himself dressed as Santa, captioning the photo as “Ozempic Santa.” However, he was actually taking Mongaru by that point (trans X).

Comedian Amy Schumer tried Ozempic for the first time in 2022, but told Andy Cohen in 2023 that it made her feel “really sick” (via Page six). In 2025, during Howard Stern’s radio show, Schumer said she was “bedridden” after losing 30 pounds (per Us Weekly). Later, she tried Wegovy, but experienced severe nausea and stopped taking the medication.

Despite the difficulty of those early experiments with GLP-1, Schumer tried Mongaro. Medication seems to be the best option. In 2025, she posted a selfie on Instagram showing her flat stomach. Schumer has gone on record to say that “Monjaro was great” (per Entertainment Weekly).

While on the podcast”Not skinny and not fatAnd in 2023, Remy Bader shared that she tried Ozempic before it became “trendy” (via NBC News). However, she didn’t take it for long before she “got a bad bulimia” and stopped taking the medication. For Badr, the result was a sudden weight gain, which is one of the reasons Things that can happen to your body when you stop taking Ozempic. Her doctor reportedly told her that her binge eating and weight issues were “100% because she went to Ozempic.”

A 2025 review eClinicalMedicine revealed that a significant proportion of obese individuals who stop taking GLP-1 end up with larger waist circumferences and higher body mass indexes (BMIs) within 12 weeks.

When hosting the 2023 Critics’ Choice Awards, comedian Chelsea Handler joked that celebrities everywhere were claiming to get skinny by drinking water, but “it’s really because everyone is using Ozempic” (via Access Hollywood). What the public didn’t know was that Handler had also tried GLP-1, with a bit of a twist.

On the “Call Her Daddy” podcast in 2023, Handler explained that she went GLP-1 without realizing it. She said one of her doctors gave her a few doses to try if she wanted to lose some weight, but she did not take it again after experiencing some of its side effects. (Read about some Celebrities who attacked Ozempic.)

Comedian Rebel Wilson has made her career playing roles centered around being a curvy woman. But she took some time out in 2020 and after to focus more on her health, which meant addressing her relationship with food with temporary help from Ozempic. She ended up getting it My physical transformation is eye-catching.

“Someone like me can have a limitless appetite for sweets, so I think these medications could be good,” Wilson explained to the media. By mid-2024, she was back on GLP-1, microdosing as a weight maintenance tool to keep her from gaining back the 80 pounds she originally lost (via USA Today).

Reality TV star Tracy Tutor didn’t hold back about her Mongaroo side effects while being interviewed on ‘Jeff Lewis has problemspodcast in 2023. The teacher revealed that GLP-1 caused her to “projectile vomit” whenever she drank alcohol.

She told Lewis she limited her use to about two months. When asked why, she said: “I didn’t want to lose any more weight, so I stopped.” However, in 2026″Mirror, mirror“I sat down with Amy Chang, and the teacher mentioned that she was still taking small doses of GLP-1s to maintain her weight.

Even after having bariatric surgery in 2013, Rosie O’Donnell needed some help managing her weight. In late 2022, she started taking GLP-1 and lost 10 pounds in about a month by taking the lowest dose of the drug, according to the British newspaper “Daily Mail”. Newsweek.

O’Donnell shared a photo of herself on Instagram in 2025, suggesting that it is still dependent on GLP-1. The photo showed her holding a microphone, and was captioned: “I can’t believe this is me now #mounjaro #weightloss #bodydismorphia.”

“Real Housewives” star Dolores Catania shared her secret to losing 20 pounds in 2023: Ozempic. Catania said American Sun She was “realistic” but wanted to reach the ultimate goal weight of 130 pounds.

While a guest on the “Virtual Reali-Tea” podcast, Catania explained that her weight loss transformation wasn’t achieved by simply taking GLP-1s (via and! news). Instead, she attributed it to a combination of medications, exercise, and being picky about the foods she ate.