The search for longevity has moved from myth to molecular science. In this eye-opening presentation, we explore groundbreaking research that reveals how telomerase activity and epigenetic modifications may hold the keys to slowing—and even reversing—the aging process.
Previously thought to function solely by extending telomeres, telomerase is now known for its unconventional roles in gene expression, mitochondrial function, and DNA repair. Emerging insights from landmark studies on the reversibility of epigenetic drift point to a future in which aging is not inevitable, but modifiable through small molecule telomerase activators.
Join Dr. Joseph Raphael and learn how these discoveries are reshaping our clinical understanding of human lifespan, healthy lifespan, and regenerative potential.
Learning objectives:
- Understand the multiple roles of telomerase in both telomere maintenance and its lesser-known functions in regulating cell biology and metabolism.
- Review the mechanisms by which epigenetic changes contribute to aging, and how partial reprogramming can restore youthful gene expression profiles.
- Analysis of results of major animal studies, including those demonstrating reversal of age-related decline through transient telomerase activation or gene resetting.
- Discuss the translational potential of these discoveries with respect to human aging, including therapeutic strategies and clinical biomarkers for rejuvenation.
Sponsored by TA Sciences
Joseph Raphael, MD He received his BA in Philosophy from Princeton University and his MD from Drexel University College of Medicine in 1989. Dr. Raphael is board certified in internal medicine and trained at New York Hospital/Weill Cornell University Medical Center. He is a diplomate of the American Board of Anti-Aging Medicine. Since 1997, he has practiced exclusively longevity medicine with an emphasis on personalized physiological age assessment and geriatric treatments. In 2007, he co-founded PhysioAge Health Analytics, a web-based vital signs data collection and reporting system now used in longevity and integrative medicine practices around the world. He has published clinical research in telomere biology, genetics, and diabetes biology. In 2015, he founded Raffaele Medical, and posts regularly about telomere biology, hormone optimization, and biomarkers for anti-aging/longevity therapies at @Raffaelemd and PhysioAge.com.
