Can your grains and food cause leaky gut?

Common medications, foods, and drinks can disrupt the integrity of our gut barrier, causing leaky gut.

Intestinal permeability, or leaky gut, may be possible He is A new target for disease prevention and treatment. With all its tiny folds, the intestinal barrier covers a surface area of ​​over 4,000 square feet—larger than a tennis court—and maintaining it requires about 40% of the body’s total energy expenditure.

There is mounting evidence involvement “Disturbance of the integrity of the intestinal barrier” in the development of a number of conditions, including celiac disease and inflammatory bowel disease. The researchers measured intestinal permeability using blue food coloring. It remained in the intestines of healthy participants but was detected in the blood of critically ill patients suffering from sepsis with damage to the intestinal barrier. However, you don’t have to end up in the ICU to develop leaky gut. Just taking some aspirin or ibuprofen can do the trick.

actually, take Taking two regular aspirin tablets (325 mg tablet) or two high-strength aspirin tablets (500 mg tablet) just once can increase leaky gut. These results indicate that even healthy people should be careful when using aspirin, because it may cause disruption of the digestive barrier.

What about buffered aspirin, a combination of aspirin and an antacid that theoretically “relieves” gastrointestinal irritation? Obviously it doesn’t make any difference: both regular aspirin and bufferin produced – Multiple erosions in the inner lining of the stomach and intestines. Researchers put an endoscope down people’s throats and saw widespread abrasion and redness within 90% of those who took aspirin or bufferin at the recommended doses. How many hours does he do this? takes To cause damage? no one. It can happen in just five minutes. acetaminophen, Sold Like Tylenol in the US, it may not damage your digestive system and may be a better option, unless you have liver problems. Instead of making things better, take vitamin C supplements back To make the aspirin-induced increase in leaky gut worse.

Interestingly, this may be the reason behind the use of NSAID medications such as aspirin, ibuprofen, and naproxen. included In up to 25% of cases of anaphylaxis caused by food. In other words, they are associated with a more than 10-fold increased risk of life-threatening food allergy attacks, and these drugs supposedly increase intestinal barrier leakage, causing small food particles to slip into the bloodstream. But can exercise also increase the risk?

Strenuous exercise can be done, for example, an hour at 70% maximum capacity. transformation So much blood gets to the muscles and away from our internal organs that it can cause transient injury to our intestines, causing mild leaky gut. But this could be it Aggravation If the athletes are taking ibuprofen or other NSAID medications, which is unfortunately very common.

Alcohol can too He is A risk factor for food allergy attacks for the same reason, which is increased leaky gut. but He cuts From alcohol, our intestines may heal.

What other food ingredients can He makes difference? High consumption of saturated fats, found in meat, dairy products and fast food, can lead to the growth of bad bacteria that produce hydrogen sulfide gas found in rotten eggs, which can lead to the breakdown of the protective mucus layer. You can see the process below and at 3:21 in my video Avoid these foods to prevent leaky gut.

that it He said It should be clear that high-fat diets in general have a negative impact on gut health by “disrupting the intestinal barrier system through a variety of mechanisms,” but most of the wide range of studies that have indicated negative effects have been conducted in laboratory animals or in a petri dish. Are people affected in the same way? You don’t know for sure until you put it to the test.

Rates of obesity and other cardiovascular disorders have more Rapidly along with the transition from traditional low-fat diets to high-fat diets. We know that disruption to our good gut flora is associated with a higher risk of many of these same diseases, and rodent studies suggest that a high-fat diet “unbalances” the microbiome while weakening the gut barrier, leading to disease. However, to connect all the dots, we need a human intervention trial, and we’ve got one: a six-month randomized controlled nutrition trial on the effects of dietary fat on the gut microbiome. It found that high fat consumption was indeed associated with unfavorable changes in the gut microbiome and pro-inflammatory factors in the blood. Note that these weren’t even primarily saturated fats, like meat and dairy. Researchers have just replaced refined carbohydrates with refined fats, replacing white rice and wheat flour with soybean oil. These results suggest that countries westernizing their diet should be advised against increasing their intake of dietary fat, while countries that have already adopted such diets should consider reducing their intake.

Doctor’s note

To learn more about leaky gut, see The leaky gut theory of why animal products cause inflammation and How to treat leaky gut with diet.

I also talked about leaky gut in my SIBO video: Friday Favorites: Tests, Fiber, and Low FODMAP for Small Intestinal Bacterial Overgrowth (SIBO).