While several Celebrities have been busy attacking Ozempic and other GLP-1 devices, Oprah Winfrey highlighted their surprising upward trend. talking to the people In December 2025, the TV icon shared that taking Ozempic helped her a lot in her sobriety journey, saying, “I was a huge fan of tequila. I literally had 17 shots one night.” “I haven’t drunk in years. The fact that I don’t want to anymore is quite amazing.”
Of course, Winfrey is not the only person who has seen this amazing benefit. A Study 2024 A study published in the Journal of Addiction found that people who were facing alcoholism and taking GLP-1 medication were 50% less likely to binge drink. After undergoing a weight-loss transformation and experiencing the benefits of sobriety that came with it, Winfrey told People magazine, “I feel more alive and energetic than ever.”
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The positive changes the talk show host has seen as a result of her health journey are clear as day in the photos taken in 2022 and 2026. In the next photo, Winfrey’s skin appears firmer and more youthful. Winfrey also seems to have developed a gorgeous glow around her face and she radiates confidence. Some of these changes can certainly be traced back to simple cosmetic tweaks or a good skin care regimen. However, there’s also the possibility that Winfrey could experience the science-backed wonders that sobriety can do for the skin.
Oprah Winfrey’s skin appears to have seen the benefits of long-term sobriety
During a December 2023 conversation with vogue india, Nutritionist Jairo Rodriguez described alcohol as “one of the worst and most aggressive compounds to destroy your skin.” He also stated that he jokingly encouraged his clients to indulge in drinking if they wanted to grow old. In April 2025 YouTube In the video, board-certified dermatologist Stephanie Capel similarly confirmed that alcohol-induced dehydration can increase signs of aging. “It impairs the skin barrier function,” Dr. Capel said. “It impairs the skin’s ability to hold water so you lose that plump vibrancy. You lose that elasticity in your skin.”
Transdermal water depletion caused by alcohol can also lead to fine lines and wrinkles. Additionally, in an April 2025 conversation with Welcome! USA, Board-certified dermatologist David Johnson shared that excessive drinking can also negatively affect collagen. Meanwhile, skincare specialist Dawn Gate confirmed that this person Appearance can change when they stop drinking alcohol. According to her, the skin can begin to compensate for alcohol-induced dryness just one week into a person’s sobriety journey. Much-needed rejuvenation can leave skin looking plump and youthful.
Dr. Johnson also mentioned that one can expect to see a reduction in skin redness, caused by alcohol-induced inflammation, about two to four weeks after their trip. According to Dr. Johnson, abstaining from alcohol for a longer period of time can give the skin a better chance of restoring collagen production. Given all this, it’s no surprise that he’s a senior Things you can do when your natural collagen levels start to decline It is to limit alcohol consumption.
